Esketamine (SPRAVATO®) Treatment

Hope Beyond Prescriptions

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What is Esketamine (SPRAVATO®)?

SPRAVATO® is an FDA-approved nasal spray medication that provides fast, temporary relief from depression symptoms during the time it takes for prescribed depression medication to take effect.

Specifically formulated to address treatment-resistant depression (TRD), SPRAVATO® operates differently from traditional antidepressants, offering a complementary approach to enhance their effectiveness.

If your antidepressant medication isn’t providing the relief you need, SPRAVATO® may be right for you.

How does Esketamine (SPRAVATO®) work?

Struggling with Depression

Esketamine (SPRAVATO®) is designed for adults with treatment-resistant depression who haven’t responded to traditional antidepressants.

Fast-Acting Relief

Administered as a nasal spray in a certified clinic under provider supervision, esketamine works differently than standard medications by targeting NMDA receptors in the brain.

Safe and Monitored Care

Each session includes observation to ensure safety and reduce side effects, while ongoing treatment helps improve mood and restore daily functioning.

BestMind gave me a second chance at living my life. They completely changed my outlook for my future and that I’ll have one. The Spravato treatment is wonderful, but the people who work with me to get it to me are the real MVPs.

Dana will go absolutely above and beyond for you and will fight to get you approved for this life changing medicine. 10/10 recommend this practice for the wonderful medicine and the even more wonderful providers.

M.E.

Spravato Patient

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What is Esketamine (SPRAVATO®)?

Esketamine (SPRAVATO®) is an FDA-approved prescription nasal spray for adults with treatment-resistant depression (TRD) or major depressive disorder (MDD) who have not improved with traditional oral antidepressants. SPRAVATO® works differently from other depression medications by targeting NMDA receptors in the brain, often delivering rapid symptom relief—sometimes within hours—that oral antidepressants cannot provide alone.

Is Esketamine (SPRAVATO®) covered by insurance at BestMind Behavioral Health?

Most major insurance plans cover Esketamine (SPRAVATO®) treatment at BestMind Behavioral Health locations throughout Oregon and Washington, including Aetna, Humana, United Healthcare, and many regional plans. Our staff at Portland, Northeast Portland, Salem, Bend, Clackamas, Eugene, and Vancouver assists with insurance verification and prior authorization for Esketamine treatment. We work with insurance providers throughout Oregon and Washington to ensure coverage for this innovative treatment-resistant depression therapy.

How is Esketamine (SPRAVATO®) administered at BestMind Behavioral Health?

Esketamine treatment at BestMind Behavioral Health is administered twice weekly for the first four weeks under direct medical supervision. Our licensed providers monitor patients throughout each Esketamine session to ensure safety and effectiveness for treatment-resistant depression. Following the initial treatment phase, maintenance dosing schedules are individualized based on treatment response throughout Oregon and Washington.

Esketamine (SPRAVATO®) Treatment Free Consultation Request